A 54-year-old female experienced short-term chest pains the day before admission. Two hours prior to admission, she reported severe chest pain radiating to her shoulders. She is hemodynamically stable with no significant arrhythmias.
Her vital signs include a blood pressure of 120/80 mmHg and a heart rate of 70 beats per minute.
Notable risk factors include hypertension, hypothyroidism, a history of smoking, menopause, and thyroid carcinoma surgery seven years ago. She has had no previous cardiovascular events. Additionally, it’s worth mentioning that her father passed away from pancreatic cancer.
ECG at admission:
TEE was preformed, EF 56%:
Lab values: Troponin 6.8, GFR 77 ml/min/1.74m2, K+ 4.6, Gly 5.5, HOL 4.9, HDL 1.82, LDL 2.39, CRP 3.2
Initial therapy: ASA 300mg, Ticagrelor 180mg, Heparin 7000 i.v., Rosuvastatin 40mg
Discharge therapy: ASA 75mg, Clopidogrel 75mg, Rosuvastatin 20mg, Bisoprolol 2.5mg , Ramipril 2.5mg, Euthyrox 100mcg
Control Coronary Angiography – 1 month after:
Initial and 1 month after
Six months following a previous episode of SCAD, the patient experienced severe chest pain radiating to both arms after strenuous activity. The patient remains hemodynamically stable with no significant arrhythmias observed.
Vital signs at the time of presentation show a blood pressure of 135/80 mmHg, a heart rate of 54 beats per minute, and a troponin level of 13.7.
TEE was preformed, EF 61%:
Discharge therapy: ASA 75mg, Clopidogrel 75mg -discontinued after a month, Rosuvastatin 20mg, Bisoprolol 2.5mg , Ramipril 2.5mg, Euthyrox 100mcg
What do you think is the reason for SCAD and ACS?
How long would you keep DAPT after the first and second events?